Novel strategies in the management of polycystic ovary syndrome.
نویسندگان
چکیده
Polycystic ovary syndrome (PCOS) is a common endocrinopathy affecting reproductive-aged women. PCOS has been recognized as a syndrome combining reproductive and metabolic abnormalities with lifelong health implications. Cardiometabolic alterations require regular screening and effective and targeted lifestyle advice to lose weight as well as to prevent weight gain. Pharmacological therapy includes insulin-sensitizer drugs and agents that act directly on metabolic comorbidities, such as statins and antiobesity drugs. Bariatric surgery may be an option for severely obese women with PCOS Regarding reproductive aspects, ovulation induction with antiestrogens such as clomiphene citrate or letrozole is the first-line medical treatment. Exogenous gonadotropins and in vitro fertilization (IVF) are recommended as second-line treatment for anovulatory infertility. Laparoscopic ovarian diathermy may be used in special cases and metformin is no longer recommended for ovulation induction. Combined oral contraceptives (OCs) are the first-line treatment for the management of menstrual irregularities in women not seeking pregnancy, also providing endometrial protection and contraception. Progestin-only pills or cyclical progestins are recommended for those with contraindications to OCs. Metformin is also considered a second-line choice for improving menstrual cycles in women presenting insulin-resistance and dysglicemia. Hirsutism requires cosmetic procedures and medical treatment with OCs. More severe cases may need anti-androgen drugs added to the OCs. In conclusion, strategies regarding the management of reproductive issues in PCOS encompass a tailored approach to individual needs of each patient.
منابع مشابه
Role of Oxidative Stress in Polycystic Ovary Syndrome
Introduction: Polycystic ovary syndrome is one of the most common causes of infertility. 6 to 8 percent of women of childbearing age have this endocrine disorder. Biochemical abnormalities in these patients lead to imbalance of female hormones and increased androgens, which can have consequences such as menstrual cycle disorder, hirsutism, acne vulgaris and androgenic alopecia. Despite the long...
متن کاملAwareness and Performance of Iranian General Practitioners in Diagnosis and Clinical Management of Polycystic Ovary Syndrome
Introduction: Polycystic ovary syndrome is very common among Iranian women. Patients with this syndrome are more likely to see general practitioners than gynecologists. This study aimed to investigate the level of knowledge and clinical management of general practitioners regarding the diagnosis and treatment of this syndrome. Materials and Methods: This cross-sectional study was performed usin...
متن کاملPmn-15: The Role of Lifestyle Modification in Management of Overweight Infertile Women with Polycystic Ovary Syndrome
Background: Polycystic ovary syndrome (PCOS) is a complex, heterogeneous disorder of uncertain etiology, with a prevalence of up to 10% and frequently associated with obesity, with at least 50% of women with polycystic ovary syndrome demonstrating overweight or obesity defined by body mass index >25 or >30 kg/m2. The syndrome is associated with numerous morbidities, including infertility, obste...
متن کاملThe Effect of Herbal Teas on Management of Polycystic Ovary Syndrome: A Systematic Review
Background & aim: Polycystic ovary syndrome (PCOS) is a common endocrine and metabolic disorder. Recently, the tendency towards complementary therapies such as using herbs with anti-androgenic effects has been increased. This study reviewed the documents related to the effect of four types of herbal teas on the treatment of PCOS based on the literature review. Methods: The searched databases in...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Minerva endocrinologica
دوره 40 3 شماره
صفحات -
تاریخ انتشار 2015